Symbol
Name
ID

Mycn
v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
MGI:97357

Phenotype annotations related to respiratory system

Darker colors indicate more annotations

Human Phenotypes	Tracheoesophageal fistula
Disease(s) Associated with MYCN	Tracheoesophageal fistula
Feingold syndrome

Mouse Phenotypes

abnormal lung morphology

abnormal lung development

abnormal branching involved in lung morphogenesis

impaired branching involved in bronchus morphogenesis

abnormal lung epithelium morphology

abnormal pulmonary alveolus epithelial cell morphology

decreased type I pneumocyte number

decreased type II pneumocyte number

pulmonary hypoplasia

absent pulmonary alveoli

respiratory distress

respiratory failure

Availability

Mouse Genotype

Mycn^tm1Jrt/Mycn^tm1Jrt

Mycn^tm1Knd/Mycn^tm1Knd

Mycn^tm1Par/Mycn^tm1Par

Mycn^tm1Jrt/Mycn^tm1Par

Mycn^tm1Nagy/Mycn^tm2.1Nagy

Tg(Sftpc-Nmyc1/EGFP)1Blh/0

Mycn^tm1Psk/Mycn^tm1Psk
Tg(Sftpc-cre)1Blh/0 (conditional)

Mycn^tm1Psk/Mycn⁺
Tg(Sftpc-cre)1Blh/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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